ABSTRACT
In this study, we aimed to evaluate the changes in laboratory parameters of COVID-19 hospitalized patients who admitted to the intensive care unit (ICU). In this retrospective study, the confirmed cases of COVID-19 patients who were hospitalized in ward and ICU from 19 January 2020 to 27 February 2020 in Firoozgar hospital, Tehran, Iran were enrolled. We analyzed clinical characteristics and laboratory findings through medical records. SPSS v.25 was used for statistical analysis. The 70 COVID-19 patients by the mean age±std. deviation 68.37±13.29 years (range 27-93 years) were carried out. The average duration of hospitalization±std. deviation was 7.4±6.17 days (7-27 days). 43 cases were male (61.4%). Fifteen patients (21.4%) did not have any underlying disease. There was significant increasing in laboratory parameters included white blood cells (p<0.0001), Creatinine (p = 0.007), aspartate aminotransferase (AST) (p = 0.050) and alanine transaminase (ALT) (p = 0.031). However, lymphocyte count was significantly decreased during hospitalization in ward before ICU-admission (p<0.0001). There was no significant difference for platelets count (p = 0.94), lactate dehydrogenase (p = 0.36), International Normalized Ratio (INR) (p = 0.114) and Partial Thromboplastin Time (PTT) (p = 0.72). Most ICU-admitted patients presented with respiratory syndrome characteristics. ICU-admitted patients had significant increase in WBC and decrease in lymphocyte count. Evidence of failure in kidney, liver function, higher activity of the coagulation system were discovered among ICU-admitted patients.
ABSTRACT
Background: In December 2019, a series of unusual pneumonia has been reported in Wuhan, China. This pneumonia was related to beta-coronavirus cluster which was named COVID-19. The aim of this study is to review the published paper on COVID-19 protections guide lines and attempt to summarize different suggested guide lines in order to help dental/oral healthcare to have better protection against COVID -19. Materials and Methods: An electronic literature search was conducted via google scholar, PubMed, and dental associations' of different countries' website using the key word "COVID-19, Dental team, Guide lines and Recommendation".A total of seven guidelines were found suitable to be included in this review. Conclusion: Individuals with 'possible' or 'confirmed' COVID-19 should not be seen for routine dental care. Multi-step approach should begin before the patient arrives on the office and includes guidance regarding their arrival and it should be completed duration of the affected patient's presence in the practice. Accurate travel history, fever or history of fever, acute respiratory infection and severe respiratory infection without fever requiring hospitalization should be checked by staff via patients telephoning to make an appointment and finally the primary infection control goal is to prevent transmission of disease. These treatment guidelines are based on very limited evidence from the literature and should be revised as soon as more evidence about the infection control advices for dental team regarding COVID-19.